Epigenetics | 
| Creators: C. David Allis, Thomas Jenuwein, Danny Reinberg, Marie-laure Caparros
Publisher: Cold Spring Harbor Laboratory Press
Category: Book
List Price: $158.00
Buy New: $126.40
You Save: $31.60 (20%)
New (17) Used (5) from $126.40
Avg. Customer Rating:  3 reviews
Sales Rank: 51394
Media: Hardcover
Edition: 1
Number Of Items: 1
Pages: 502
Shipping Weight (lbs): 3.6
Dimensions (in): 11.3 x 8.6 x 1.1
ISBN: 0879697245
Dewey Decimal Number: 572.865
EAN: 9780879697242
ASIN: 0879697245
Publication Date: October 31, 2007
Shipping: Eligible for Super Saver Shipping
Availability: Usually ships in 24 hours
|
| Similar Items:
|
| Editorial Reviews:
Product Description
The regulation of gene expression in many biological processes involves epigenetic mechanisms. In this new volume, 24 chapters written by experts in the field discuss epigenetic effects from many perspectives. There are chapters on the basic molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of organisms in which it has been most studied. Thus, there are chapters on histone and DNA methylation, siRNAs and gene silencing; X-chromosome inactivation, dosage compensation and imprinting; and discussion of epigenetics in microbes, plants, insects, and mammals. The last part of the book looks at how epigenetic mechanisms act in cell division and differentiation, and how errors in these pathways contribute to cancer and other human diseases. Also discussed are consequences of epigenetics in attempts to clone animals. This book is a major resource for those working in the field, as well as being a suitable text for advanced undergraduate and graduate courses on gene regulation.
Related Titles from the Publisher
Binding and Kinetics for Molecular Biologists;
Bioinformatics;
The Condensed Protocols From Molecular Cloning: A Laboratory Manual;
Discovering Genomics, Proteomics, and Bioinformatics, 2e;
DNA Replication and Human Disease;
DNA Science;
Epigenetics;
Genes and Signals;
Gene Transfer: Delivery and Expression of DNA and RNA, A Laboratory Manual;
Genetic Variation;
Genomes;
Molecular Biology, 6th Edition;
Recombinant DNA: Genes and Genomes - A Short Course;
The RNA World
|
| Customer Reviews:
Epigenetics - a timely and important text. May 14, 2007
5 out of 5 found this review helpful
It is becoming clear that epigenetic mechanisms are responsible for a large number of "genetic" events in the organism, both under normal and pathological circumstances. This advanced text (suitable for advanced undergraduates and beginning graduate students) brings together, in a very readable way, the various mechanisms of epigenetic heredity.
An invaluable educational tool April 11, 2007
6 out of 6 found this review helpful
Epigenetics is a scientific textbook written to teach advanced undergraduate and graduate college students about epigenetic mechanisms, which regulate gene expression in many biological processes. Chapters cover histone modifications, chromatin remodeling, DNA methylation, siRNAs and gene silencing, X-chromosome inactivation, epigenetics in microbes, plants, insects and mammals, and much more. An in-depth, scholarly, and informative instructional reference, interspersed with occasional color photographs and diagrams, featuring an extensive list of references and a general summary at the end of each chapter to aid comprehension. An invaluable educational tool for specialized college science courses, as well as for professionals in the field of biology seeking to sharpen their understanding of modern epigenetics.
Represents the Current State of the Art December 18, 2006
10 out of 15 found this review helpful
Wikipedia says: 'Epigenetics is the study of epigenetic inheritance, a set of reversible heritable changes in gene function or other cell phenotype that occur without a change in DNA sequence (genotype).'
That's a pretty general definition, and you can get into some pretty good arguments that this or that word should be changed.
The fundamental discoveries that began the field began to be discussed in 1941, but it grew slowly until fairly recent years. By 2004 the science had developed enough that the 69th Cold Spring Harbor Symposium on Quantitative Biology covered the topic. Many of the authors of this book attended that symposium and the seeds for this book were sown.
The book was written by about forty of the preeminent researchers in the field. It consists of 24 chapters covering virtually all known aspects of the subject. It can serve as a reference work for the current state of the art, or could be used as a text for advanced undergraduate or graduate courses on gene regulation.
|
|
|
